Updated 28 August 2018

Draft Programme
NuGO week 2018 – Mitochondria, nutrition and health

Monday, 3rd  September
16.00  Start registration
17.30  Opening NuGO week 2018
Chair: Prof John Mathers
Prof John Mathers, Chair NuGOweek 2018,  Newcastle University, UK
Prof David Burn, Pro-Vice-Chancellor of Medicine, Newcastle University, UK
Welcome and opening
18.00  Prof Sir Doug Turnbull, Newcastle University, UK; Mitochondria in health and disease
18.45  Introduction of new NuGO member organisations

19.15   Welcome reception

Tuesday, 4th  September
Session 1:  Mitochondrial function in health and disease
Chair: Dr Guy Vergeres
09.00  Prof Patrick Schrauwen, University of Maastricht, NL;  Mitochondrial (dys)function in skeletal muscle and its role in type 2 diabetes
09.40  Dr Camilla Bean, University of Padua, IT;  Keeping mitochondria in shape: a matter of life, death and metabolism
10.20  Coffee break

Chair: Prof Diana Ivanova
10.50 Stella Breiningen, University of Newcastle, UK; Effect of weight loss on mitochondrial defects in the ageing human colon.
11.10 Pieter Giesbertz, Technical University Munich, DE; A congestion model of substrates for NAD+- and FAD-dependent reactions explaining metabolite profiles observed in murine and human type 1 diabetes.
11.30 Federico Bernuzzi, Quadram Institute of Bioscience, UK; Regulation of mitochondrial bioenergetics by the food-derived bioactive sulforaphane through activation of NRF
11.50 Kieran Finney, University of Newcastle, UK; The effect of chronic high dose Vitamin A on Lipid metabolism, in a pig model

12.10  Poster session 1

13.00  Lunch and continue of poster session 1

14.00  Social event (several options will be offered to discover Newcastle)

16.00  Coffee break

Session 2: Assessing Mitochondrial function
Chair: Dr Lydia Afman
16.30  Prof Karsten Hiller, Technical University Braunschweig, DE; Profiling mitochondrial metabolism
17.10  Marie Joe Dib, University of Surrey, UK; Functional vitamin B12 status (cB12) and mitochondrial (dys)function

Session 3:  Joint Programming Initiative ‘a Healthy Diet for a Healthy Life’ (JPI HDHL): The Food Biomarkers  Alliance (FoodBALL)
Chair: Prof Richard Mithen
17.30  Prof Edith Feskens, Wageningen University & Research, NL; FoodBall Finals – Results of  a project on biomarkers of food intake
18.10  Caroline Rombouts, Ghent University, BE; Untargeted metabolomics of in vitro human and in vivo pig colonic digests reveals putative biomarkers associated with red or white meat intake
18.30 Nathalia Vázquez-Manjarrez, University of Copenhagen, DK; Bananomics: discovery and validation of intake biomarkers for banana, a naturally bioactive food
18.50 Elise Nordin, Chalmers University of Technology, SE; Identification of IBS metabotypes based on physiological responses to food


Wednesday 5th September

Session 4:  Approaches to complexity
Chair: Prof Michael Müller
09.00  Dr Baruch Barzel, Bar-Ilan University, IL; Biological applications of complex network science
09.40  Prof John Chambers, Lee Kong Chian School of Medicine, Singapore; Genotypes, epitypes, metabotypes and heath
10.20  Coffee break

Chair: Dr Jill McKay
10.50  Prof Marjo-Riitta Jarvelin, Imperial College London, UK; DynaHEALTH project – Systematic bio-psychosocial modelling of glycaemic health
11.30   Prof Lothar Rink, RWTH Aachen University, DE; Zinc homeostasis as a gatekeeper of immune response

12.10  Poster session 2

13.00  Lunch

Chair: Prof Lynn Vanhaecke
14.00 Brian J. Bennet, University of California Davis, US; Systems Genetic approaches to studying metabolic complexity
14.20 Chiara Murgia, Monash University, AU; Modulation of molecular circadian clock by meal timing and composition
14.40 Stine Marie Ulven, University of Oslo, NO; Using metabolic profiling to explore molecular effects of replacing saturated fat with polyunsaturated fat- a randomized controlled dietary intervention study
15.00 Short break

Session 5:  Early career investigators
Chairs: Siva Charan Sri Harsha Pedapati and Charlotte Michielsen
15.15  Sarah Coshi, University of Newcastle, UK; Mitochondrial DNA methylation level as a predictor of future cardiovascular outcome in an obese population
15.35 Bart Langewaard, Wageningen University & Research, NL; Novel method for non-invasive assessment of muscle mitochondrial function in healthy, young males and its relation to parameters of aerobic fitness.
15.55 Harry Freitag Luglio Muhammad, Universitas Gadjah Mada, Indonesia/ Maastricht University, NL; The association between the inflammatory properties of the diet and blood pressure and its interaction with Uncoupling Protein 2 gene variation
16.15  Iris de Hoogh, TNO, NL; Blood glucose, cognition, and wellbeing in relation to food intake @ work
16.35
 Tamiris Barros, University of São Paulo, BR, Nutrient status and DNA damage in Brazilian children and adolescents
16.55  Short break

Session 6:  Bioinformatics tools
Chair: Prof Chris Evelo
17.10  Dr Anthony Mathelier, Centre for Molecular Medicine Norway, NO; Introduction to Jaspar and related tools
17.40  Kathryn Burton, Agroscope, CH; Network-based strategies to associate changes in postprandial gene expression in whole blood with circulating biomarkers
18.00 Susan Coort, Maastricht University, NL; Pathway and network analysis for 1,25-dihydroxyvitamin D3

19.30  Conference dinner at the Assembly Rooms

Thursday 6th September
Chair: Prof Michael Fenech

Session 7:  Epigenetic effects of micronutrients and their impact on cellular and mitochondrial metabolism
09.00 Prof Susan Duthie, Robert Gordon University Aberdeen, UK; Epigenetics and the exposome: the impact of diet on the epigenome and human cancer risk
09.30 Prof Carsten Carlberg, University of Eastern Finland, FI; Epigenetic effects of vitamin D
10.00 Coffee break

Chair: Dr Chiara Murga
10.30  Dr Sara Pauwels, University of Leuven, BE; Methyl-group donors and the epigenome
11.00  Dr Gaofeng Wang, University of Miami, US; The epigenetic role of vitamin C in cancer treatment
11.30  Chanachai Sae-Lee, University of Newcastle, UK; Dietary intervention modifies DNA methylation age assessed by the epigenetic clock
11.45 Sandra G. Heil, Erasmus University Medical Center, NL; Association of dietary folate and vitamin B12 intake with genome-wide DNA methylation; a large scale epigenome-wide association analysis in 5,841 individuals

12.00  Lunch

Chair: Dr André Mazur
13.00 Prof Ram Reifen, Hebrew University of Jerusalem, IL; Epigenetic effects of vitamin A
13.30 Prof Chris Evelo, Maastricht University, NL; Micronutrient effects on the epigenome, non-coding RNA, network analysis and visualisation
14.00 Prof Anna Kipp, Friedrich Schiller University Jena, DE; Epigenetic effects of the trace element selenium
14.30 Short break

Chair: Prof John Mathers
14.45 Prof Michael Fenech, Foundation President of the Asia-Pacific Nutrigenomics and Nutrigenetics Organisation (APNNO); Wrap-up session 7
15.15  Closing session NuGO week 2018
– Wrap-up NuGO week 2018
– Announcement NuGO week 2019
– Close and depart

NuGO