Just as the entire DNA sequence is called the human genome so the full complement of proteins in a cell or tissue is called the proteome. Subsets of proteins from the proteome will be produced by different cells and these will change in response to internal and external stimuli.

Proteomics is the study of the proteome, and attempts to determine the role of the proteins found in cells, tissues or an organism at any one time. Proteomics is technically very challenging and the presence/ absence of protein is not necessarily indicative of metabolic change.

Publications

Proteomics in nutrition research - Fuchs et al., 2005 BJN 94: 302–314

Other publications:

• Fu et al. Proteomics (2005) 5: 2656-2664 (intra-/ inter-individual variation in plasma)

Detecting the effects of dietary manipulation:

• Hittel et al. Diabetes (2005) 54: 1283-88 (skeletal muscle in lean and obese women)
• Mitchell et al. Proteomics (2005) 5: 2238-2246 (effects of broccoli consumption)