The transcriptome is the complete set of RNA products that can be produced from the genome, and transcriptomics is the study of the transcriptome. Microarrays and chips represent powerful tools for studies of diet-gene interactions. "Their use, however, is still associated with a number of technical challenges as well as questions about biological significance" (Garosi et al., 2005)

Publications:

Baseline gene behaviour in apparently healthy humans

• Whitney et al., 2003 Proc Natl Acad Sci USA 100: 1896-1901
• Radich et al., 2004 Genomics 83: 980-988
• Eady et al., 2005 Physiol Genomics. 22:402-11
  

Detecting the effects of dietary manipulation

• Dahlman et al., 2005 Am J Clin Nutr 81: 1275-85 (caloric restriction)
• Clément et al., 2004 FASEB J 18: 1657-69 (caloric restriction and inflammation)

Best practice and standard operating procedures

• Garosi et al., 2005 BJN 93: 425-432